Manchester United will be looking for their first home win of the Premier League season when they welcome Chelsea to Old Trafford on Saturday.
Ole Gunnar Solskjaer relieved some of the pressure on his shoulders with another big win away at Paris Saint-Germain, but it is at home, and domestically, where United have been somewhat lacking this term.
The weekend kicks off on Friday day as Aston Villa look to go top of the league by beating Leeds United. Saturday begins at the London Stadium where West Ham will look to build upon three good recent results when Manchester City visit.
Fulham and Crystal Palace meet in a London derby before United host Chelsea. Premier League champions Liverpool see out the day at home to Sheffield United.
Everton will look to continue their run away at Southampton in Sunday’s early game, before Wolves host Newcastle and Arsenal welcome Leicester City to north London. Monday sees West Brom at Brighton before Tottenham visit Burnley in the final game.
Gameweek 6 fixtures and results
|Friday, October 23||Kick-off||How to watch|
|Aston Villa vs Leeds||8pm||BT Sport Box Office|
|Saturday, October 24|
|West Ham vs Man City||12.30pm||BT Sport|
|Fulham vs Crystal Palace||3pm||BT Sport Box Office|
|Man United vs Chelsea||5.30pm||Sky Sports|
|Liverpool vs Sheffield United||5.30pm||Sky Sports Box Office|
|Sunday, October 25|
|Southampton vs Everton||2pm||Sky Sports|
|Wolves vs Newcastle||4.30pm||Sky Sports|
|Arsenal vs Leicester||7.15pm||Sky Sports Box Office|
|Monday, October 26|
|Brighton vs West Brom||5.30pm||Sky Sports Box Office|
|Burnley vs Tottenham||8pm||Sky Sports|
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