Victor Lindelof and Luke Shaw were also ruled out before the game, and the United boss will also have to check on Eric Bailly after he suffered a blow to the head during the match.
Pogba’s 2019-20 season was marred by an ankle injury which required surgery and kept him out of action for many weeks.
Paul Pogba was not in the squad for Man United’s Saturday FA Cup match due to injury
He also had a spell on the side lines this season, missing a few games due to an ankle problem he picked up on international duty with France.
Manchester United face a big week ahead. They can go top of the league with a win against Burnley and will then face rivals Liverpool, so Solskjaer will be hoping there are no long term injuries to contend with.
Solskjaer’s happiness at making it through to the FA Cup fourth round was tinged by disappointment at his much-changed side’s display against Watford.
Having fallen to a galling loss to rivals Manchester City in Wednesday’s Carabao Cup semi-final, Scott McTominay’s early header secured a 1-0 win against Sky Bet Championship opposition in Saturday evening’s third-round encounter.
Ole Gunnar Solskjaer will be hoping for full fitness with a big week coming up for United
United flew out of the blocks at an empty Old Trafford but dropped off markedly, with the nine players brought into the side leading to a lack of fluency and unconvincing display.
‘Very happy to get through,’ Solskjaer said. ‘We started very brightly.
‘I expected it to be other way round – that we needed 15-20 minutes to get going and find our rhythm.
‘But after a very good start we lost our shape, we lost too many balls.
‘We lost it easily. It was like we started making difficult decisions to try and complicate things and maybe show the manager that ‘I want to play in the next game’.
Pogba’s last couple of seasons have been marred by injuries, particularly related to his ankle
‘I know they’re good players so they didn’t have to do that, but we’re through. That’s the main thing.’
Donny Van De Beek, Brandon Williams and Jesse Lingard were among the alterations, with Dean Henderson and McTominay the only players retaining a starting spot from the City loss.
The latter proved the difference on Saturday evening, when leading United out as captain for the first time.
‘He’s got great character, good attitude,’ Solskjaer said of academy graduate McTominay. ‘He comes in every day, does the right things, lives his life properly, wants to be the best he can be and he’s not afraid to be vocal.
‘He always, always goes out there to give his best. Never shirks a tackle. Nothing.
Eric Bailly will also need to be checked after he took a blow to the head against Watford
‘He’s got everything a leader has to have, so I just wanted to test him today how he reacted because he always done that anyway.
‘But I gave him the armband to see if there was any change in him but luckily there wasn’t.’
On a night of few highlights, the main concern was the blow that forced Eric Bailly off towards the end of the first half.
Having been hit in the back of the head when goalkeeper Henderson was clearing a ball, Solskjaer said when asked for an update: ‘I honestly can’t tell you.
‘I think he got a good whack. I don’t think it’s concussion. I think it’s his neck, which is sore.
Manchester United got the win against Watford, although they were not convincing at times
‘Hopefully a muscle injury but we’ll have to check him tomorrow and fingers crossed he won’t be out for too long.’
Watford return to action at home to Huddersfield in the Championship next weekend after putting in a performance that pleased recently-appointed boss Xisco Munoz.
‘I’m very proud of our players,’ he said after his third match in charge of the Hornets. ‘This is our style.
‘I know we have little details to improve. We know we have a very good team against us.
‘The guys give us very good intensity, with very good tactics.
‘Our team is growing up and it’s important we believe in our team.’